For three significant figures, the SAS Institute provides the following code snippet to accomplish the task. However, it is often useful to round to more or less than 3 significant figures. I’ve developed a macro to do so for my own use and am sharing the code below.
I’m making available here a basic NONMEM dataset example, along with the R code used to create it. Hopefully it will be helpful to someone in future! CSV download: http://jvdl.me/downloads/nonmem/dummy_nonmem.csv XPT download: http://jvdl.me/downloads/nonmem/dummy_nonmem.xpt
One-time-pad encryption offers unbreakable* security if you can guarantee truly random number generation and security of the generated pad. Implementing it from the perspective of a cryptographic layman is a fun way to learn more about it and could add an extra layer of security to your most sensitive communications. I started off by trying […]
For the most part, experienced SAS programmers know where to look for the source data they need. In the pharmaceutical industry, we are familiar with CDISC standards and data structures. However, should the data standard be unfamiliar or the source datasets include new or unusual parameters, it may be prudent to have SAS look through […]
ADDL represents the number of additional doses that are copies of the current row, with the time since first dose (RTFD) increased at the regular dosing interval (II). This allows for the compression of dose records in the NONMEM dataset. To put it more eloquently: The NONMEM data item ADDL on a dose record expresses […]